Yeah, I have 20 to be exact, my favorite is my 450 Marlin. Its light, compact, and cuts trees down if they get in the way. Great Bear gun, really thumps em, and should you hit bone, it still penetrates deep enough for a clean kill.
I used to have a 416 Rigby, but I got rid of it because they didnt sell a shoulder replacement kit with it lol!! Its Safari Grade, made for Plains game, would be a heck of a Moose gun.
For varmints I prefer my 243 and 223, they are flat shooting and when tipped with hollow points, they really explode on impact. All the calibers I shoot, I usually go with the lightest grain bullet I can get and use ballistic tips, Hornady sst's, or fail safe rounds, except for the Marlin of course, they have limited choices.